4D embryonic cardiography using gated optical coherence tomography.

  title={4D embryonic cardiography using gated optical coherence tomography.},
  author={Michael W. Jenkins and Florence G. Rothenberg and Debasish Roy and Vladimir Nikolski and Zhilin Hu and Michiko Watanabe and David L. Wilson and Igor R. Efimov and Andrew M. Rollins},
  journal={Optics express},
  volume={14 2},
Simultaneous imaging of very early embryonic heart structure and function has technical limitations of spatial and temporal resolution. We have developed a gated technique using optical coherence tomography (OCT) that can rapidly image beating embryonic hearts in four-dimensions (4D), at high spatial resolution (10-15 mum), and with a depth penetration of 1.5 - 2.0 mm that is suitable for the study of early embryonic hearts. We acquired data from paced, excised, embryonic chicken and mouse… CONTINUE READING
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