4D Super-Resolution Microscopy with Conventional Fluorophores and Single Wavelength Excitation in Optically Thick Cells and Tissues

@inproceedings{Baddeley20114DSM,
  title={4D Super-Resolution Microscopy with Conventional Fluorophores and Single Wavelength Excitation in Optically Thick Cells and Tissues},
  author={David Baddeley and David H. Crossman and Sabrina Rossberger and Juliette E. Cheyne and Johanna M Montgomery and Isuru D Jayasinghe and Christoph Cremer and Mark B. Cannell and Christian Soeller},
  booktitle={PloS one},
  year={2011}
}
BACKGROUND Optical super-resolution imaging of fluorescently stained biological samples is rapidly becoming an important tool to investigate protein distribution at the molecular scale. It is therefore important to develop practical super-resolution methods that allow capturing the full three-dimensional nature of biological systems and also can visualize multiple protein species in the same sample. METHODOLOGY/PRINCIPAL FINDINGS We show that the use of a combination of conventional near… CONTINUE READING