489 DECREASE IN GROWTH HORMONE (GH) AND SOMATOMEDIN (SOMC) DURING LHRH AGONIST (LHRHa) TREATMENT OF CENTRAL PRECOCIOUS PUBERTY (CPP)

Abstract

LHRHa suppresses both gonadotropin pulsations and sex steroids and slows height velocity (HV) in patients with CPP. To evaluate GH's role in this slowing of growth, sleep induced GH secretion (20 min samples, 10 PM – 2 AM) and SOMC (10 PM) were measured in 9 pre-adrenarchal girls with CPP (ages at onset 1.6–6.3 yrs, M=3.8; bone ages advanced a mean of 3.7… (More)
DOI: 10.1203/00006450-198504000-00519

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@article{Rudlin1985489DI, title={489 DECREASE IN GROWTH HORMONE (GH) AND SOMATOMEDIN (SOMC) DURING LHRH AGONIST (LHRHa) TREATMENT OF CENTRAL PRECOCIOUS PUBERTY (CPP)}, author={Craig R Rudlin and Maynard J. Mansfield and John E Crigler and Karin A Karol and John P Crawford and Paul A. Boepple and William E Crowley}, journal={Pediatric Research}, year={1985}, volume={19}, pages={192A-192A} }