47,Xxx in an adolescent with premature ovarian failure and autoimmune disease

@article{Holland200047XxxIA,
  title={47,Xxx in an adolescent with premature ovarian failure and autoimmune disease},
  author={Holland},
  journal={Journal of pediatric and adolescent gynecology},
  year={2000},
  volume={13 2},
  pages={93}
}
  • Holland
  • Published 2000 in Journal of pediatric and adolescent gynecology
Background: Premature ovarian failure (POF) is often associated with autoimmune disorders. The 47,XXX karyotype has also been associated with POF and other genitourinary abnormalities. Following is a case of a 17 year old with immune thrombocytopenic purpura (ITP), POF, 47, XXX and a positive antinuclear antibody (ANA).Case Report: A 17 year old Caucasian female was referred to the Adolescent Health Clinic for evaluation of oligomenorrhea with secondary amenorrhea. Thelarche occurred at 12… CONTINUE READING