4-repeat tauopathy sharing pathological and biochemical features of corticobasal degeneration and progressive supranuclear palsy

@article{Katsuse20034repeatTS,
  title={4-repeat tauopathy sharing pathological and biochemical features of corticobasal degeneration and progressive supranuclear palsy},
  author={O Katsuse and Eizo Iseki and Tetsuaki Arai and Haruhiko Akiyama and Takashi Togo and Hirotake Uchikado and Masanori Kato and Rohan de Silva and Andrew John Lees and Ken-ichi Kosaka},
  journal={Acta Neuropathologica},
  year={2003},
  volume={106},
  pages={251-260}
}
We report a 67-year-old man with 4-repeat (4R) tauopathy sharing both features of corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP). Although CBD and PSP have a common pathological feature that 4R tau accumulates in neurons and glia, recent pathological studies have confirmed differences between the two disorders. Clinical features of the present case were asymmetrical apraxia, parkinsonism, memory disturbance, disorientation and left limb myoclonus with a 5-year history… Expand
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