• Corpus ID: 43735211

4-Hydroxyphenylpyruvate dioxygenase from pig liver.

@article{Buckthal19874HydroxyphenylpyruvateDF,
  title={4-Hydroxyphenylpyruvate dioxygenase from pig liver.},
  author={David J. Buckthal and Patrick A. Roche and Thomas John Moorehead and Brian Forbes and Gordon A. Hamilton},
  journal={Methods in enzymology},
  year={1987},
  volume={142},
  pages={
          132-8
        }
}
Scavenging properties of neutrophil 4-hydroxyphenylpyruvate dioxygenase are based on a hypothesis that does not stand up to scrutiny.
Tyrosinaemia type III: Immunochemical studies on 4-hydroxyphenylpyruvic acid dioxygenase and molecular cloning of cDNA for the enzyme
TLDR
To better comprehend structure-function relationships, gene organization and biosynthetic regulatory mechanisms, the 4HPA dioxygenase gene is of interest with regard to type I tyrosineemia and type III tyrosinaemia.
Inhibition of Barnyardgrass 4-Hydroxyphenylpyruvate Dioxygenase by Sulcotrione
4-Hydroxyphenylpyruvate dioxygenase (EC 1.13.1 1.27) was partially purified from barnyardgrass (Fchinochloa crus-galli 1.) leaves and assayed by high-performance liquid chromatography analysis of
In vivo correction with recombinant adenovirus of 4-hydroxyphenylpyruvic acid dioxygenase deficiencies in strain III mice.
TLDR
The intravenous administration of the adenoviral vector bearing a foreign gene seems suitable for transient, early gene transfer into the liver in tyrosinemia type 3 mice.
Inhibition of Barnyardgrass 4-Hydroxyphenylpyruvate Dioxygenase by Sulcotrione
TLDR
The bleaching herbicide sulcotrione [2-chloro-4-methanesulfonylbenzoyl)-1,3-cyclohexanedione] was shown to be a potent, linear competitive inhibitor of 4-hydroxyphenylpyruvate dioxygenase.
A murine model for type III tyrosinemia: lack of immunologically detectable 4-hydroxyphenylpyruvic acid dioxygenase enzyme protein in a novel mouse strain with hypertyrosinemia.
TLDR
Analysis of this mutant strain of mouse is expected to provide valuable information on the pathogenesis of human type III tyrosinemia and can also serve as a useful system for studies on tyrosine metabolism.