4-Hydroxy-2-nonenal: a critical target in oxidative stress?


In this perspective, we summarize and discuss critical advancements in the study of 4-hydroxy-2-nonenal (4-HNE) as it relates to diseases and clinical complications either caused or exacerbated by oxidative stress. Since its identification in 1980, 4-HNE has been extensively studied with an emphasis on its formation, its role in pathology, and its targets… (More)
DOI: 10.1152/ajpcell.00101.2016


Cite this paper

@article{Breitzig20164Hydroxy2nonenalAC, title={4-Hydroxy-2-nonenal: a critical target in oxidative stress?}, author={Mason T. Breitzig and Charishma Bhimineni and Richard Anthony Lockey and Narasaiah Kolliputi}, journal={American journal of physiology. Cell physiology}, year={2016}, volume={311 4}, pages={C537-C543} }