4-Aminopyridine improves pulmonary function in quadriplegic humans with longstanding spinal cord injury.

@article{Segal19974AminopyridineIP,
  title={4-Aminopyridine improves pulmonary function in quadriplegic humans with longstanding spinal cord injury.},
  author={Jack L. Segal and Sherry R. Brunnemann},
  journal={Pharmacotherapy},
  year={1997},
  volume={17 3},
  pages={415-23}
}
STUDY OBJECTIVE To test the hypothesis that 4-aminopyridine (4-AP) might cause clinically evident improvement in pulmonary function in humans with chronic spinal cord injury (chronic SCI). DESIGN Balanced, open-label study with subjects consecutively enrolled. SETTING Spinal Cord Injury Service, university-affiliated tertiary level care Department of Veterans Affairs Medical Center. PATIENTS Seventeen healthy men and women suffering from traumatic SCI (11 quadriplegic, 6 paraplegic… CONTINUE READING