• DOI:10.1042/BJ1660017
Corpus ID: 34240809

4,4'-dimethylcholesta-7,9,14-trienol is an intermediate in the demethylation of dihydroagnosterol.

@article{Tavares197744dimethylcholesta7914trienolIA,
  title={4,4'-dimethylcholesta-7,9,14-trienol is an intermediate in the demethylation of dihydroagnosterol.},
  author={I. Tavares and K. Munday and D. Wilton},
  journal={The Biochemical journal},
  year={1977},
  volume={166 1},
  pages={
          17-20
        }
}

I. Tavares, K. Munday, D. Wilton

Published 1977

Chemistry, Medicine

The Biochemical journal

1. 4,4'-Dimethylcholesta-7,9,14-trienol is an intermediate in the metabolism of dihydroagnosterol to cholesterol by rat liver homogenate. 2. This triene is reduced by a rat liver microsomal preparation in the presence of NADPH to give 4,4'-dimethylcholesta-7,9-dienol under anaerobic conditions. 3. Reduction of the triene in the presence of [4-3H2]NADPH resulted in the incorporation of 3H into the product. 4. Under aerobic conditions the triene is converted into cholesterol by a rat liver… CONTINUE READING

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