3p22.1 and 10q22.3 deletions detected by fluorescence in situ hybridization (FISH): a potential new tool for early detection of non-small cell lung Cancer (NSCLC).

@article{Yendamuri20083p221A1,
  title={3p22.1 and 10q22.3 deletions detected by fluorescence in situ hybridization (FISH): a potential new tool for early detection of non-small cell lung Cancer (NSCLC).},
  author={Sai S Yendamuri and Ara Asadur Vaporciyan and Tanweer M Zaidi and Lei Feng and Ricardo L{\'o}pez Fern{\'a}ndez and N. Benjamin Bekele and Wayne Lewis Hofstetter and Feng Jiang and Reza John Mehran and David Rice and Margaret R. Spitz and Stephen G Swisher and Garrett Lyndon Walsh and J. L. A. Roth and Ruth L. Katz},
  journal={Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer},
  year={2008},
  volume={3 9},
  pages={979-84}
}
BACKGROUND Our objective was to study the feasibility of detecting chromosomal deletions at 3p22.1 and 10q22.3 by fluorescent in situ hybridization (FISH) and to examine their distribution in different areas of the airway in patients with non-small cell lung cancer. METHODS Brush biopsies from the mainstem bronchus on the normal side contralateral to the tumor (NBB) and mainstem bronchus on the tumor side (TBB) were obtained from 122 patients who underwent surgical resection. Touch… CONTINUE READING
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