3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain

@article{Hill19813HbaclofenA3,
  title={3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain},
  author={David R. Hill and Norman G. Bowery},
  journal={Nature},
  year={1981},
  volume={290},
  pages={149-152}
}
The presence of a novel receptor for the neurotransmitter γ-aminobutyric acid (GABA) on peripheral autononric nerve terminals and in mammalian brain slices has been described recently1–4. This receptor differs from the classical GABA site as it is unaffected by recognized GABA antagonists such as bicuculline and is not sensitive to the majority of accepted GABA-mimetics such as 3-aminopropanesulphonic acid (3-APS) or isoguvacine. We propose to designate the classical site as the GABAA and the… Expand
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