3D visualization of extracellular vesicle uptake by endothelial cells

@inproceedings{DurakKozica20183DVO,
  title={3D visualization of extracellular vesicle uptake by endothelial cells},
  author={Martyna Durak-Kozica and Zbigniew Baster and Karol Kubat and Ewa Ł Stępień},
  booktitle={Cellular & Molecular Biology Letters},
  year={2018}
}
BackgroundExtracellular vesicles are small vesicles that contain cytoplasmic and membrane components from their paternal cells. They enter target cells through uptake to transfer their biological cargo. In this study, we investigated the process of endothelial EV internalization and created a 3D visualization of their intracellular distribution.Methods and resultsTwo immortalized endothelial cell lines that express h-TERT (human telomerase) were used for EV release: microvascular TIME and… CONTINUE READING
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