3D reconstruction of mammalian septin filaments.

  title={3D reconstruction of mammalian septin filaments.},
  author={Natalya Lukoyanova and Stephen A. Baldwin and John Trinick},
  journal={Journal of molecular biology},
  volume={376 1},
Mammalian septins are a family of guanosine triphosphate-binding proteins thought to play a role in a number of key cellular processes, such as cytokinesis, protein scaffolding and vesicle trafficking. Although their precise functions remain to be determined, electron microscopy has shown septin filament formation in vitro and a role as a cytoskeletal polymer has been proposed. Here, we present a 3D reconstruction of septin filaments determined using electron microscopy of negatively stained… CONTINUE READING


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. 3 D reconstruction of mammalian septin filaments

  • N Lukoyanova, SA Baldwin, J Trinick
  • J Mol Biol

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