3D reconstruction and capsid protein characterization of grass carp reovirus

@article{Fang20053DRA,
  title={3D reconstruction and capsid protein characterization of grass carp reovirus},
  author={Qin Mei Fang and Sanket U Shah and Yuyao Liang and H. Z. Zhou},
  journal={Science in China Series C: Life Sciences},
  year={2005},
  volume={48},
  pages={593-600}
}
Grass carp reovirus (GCRV) is a relatively new virus first isolated in China and is a member of the Aquareovirus genus of the Reoviridae family. Recent report of genomic sequencing showed that GCRV shared high degree of homology with mammalian reovirus (MRV). As a step of our effort to understand the structural basis of GCRV pathogenesis, we determined the three-dimensional (3D) structure of GCRV capsid at 17 Å resolution by electron cryomicroscopy. Each GCRV capsid has a multilayered… CONTINUE READING