3D printed tablets loaded with polymeric nanocapsules: An innovative approach to produce customized drug delivery systems.

@article{Beck20173DPT,
  title={3D printed tablets loaded with polymeric nanocapsules: An innovative approach to produce customized drug delivery systems.},
  author={Ruy Carlos Ruver Beck and Paula dos Santos Chaves and Alvaro Goyanes and Branko Vukosavljevic and Asma B. M. Buanz and Maike Windbergs and Abdul W. Basit and Simon Gaisford},
  journal={International journal of pharmaceutics},
  year={2017},
  volume={528 1-2},
  pages={268-279}
}
The generation of multi-functional drug delivery systems, namely solid dosage forms loaded with nano-sized carriers, remains little explored and is still a challenge for formulators. For the first time, the coupling of two important technologies, 3D printing and nanotechnology, to produce innovative solid dosage forms containing drug-loaded nanocapsules was evaluated here. Drug delivery devices were prepared by fused deposition modelling (FDM) from poly(ε-caprolactone) (PCL) and Eudragit® RL100… CONTINUE READING
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