3D micron-scale imaging of the cortical bone canal network in human osteogenesis imperfecta (OI)

@inproceedings{Jameson20133DMI,
  title={3D micron-scale imaging of the cortical bone canal network in human osteogenesis imperfecta (OI)},
  author={John Jameson and Carolyne I Albert and Bjoern Busse and Peter A. Smith and Gerald F. Harris},
  booktitle={Medical Imaging},
  year={2013}
}
Osteogenesis imperfecta (OI) is a genetic disorder leading to increased bone fragility. Recent work has shown that the hierarchical structure of bone plays an important role in determining its mechanical properties and resistance to fracture. The current study represents one of the first attempts to characterize the 3D structure and composition of cortical bone in OI at the micron-scale. A total of 26 pediatric bone fragments from 18 individuals were collected during autopsy (Nc=5) or routing… Expand
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  • Chemistry, Medicine
  • Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
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TLDR
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