3D in utero quantification of T2* relaxation times in human fetal brain tissues for age optimized structural and functional MRI.

@article{Blazejewska20173DIU,
  title={3D in utero quantification of T2* relaxation times in human fetal brain tissues for age optimized structural and functional MRI.},
  author={Anna I Blazejewska and Sharmishtaa Seshamani and Susan Mckown and Jason Caucutt and Manjiri K Dighe and Christopher Gatenby and Colin Studholme},
  journal={Magnetic resonance in medicine},
  year={2017},
  volume={78 3},
  pages={
          909-916
        }
}
PURPOSE Maximization of the blood oxygen level-dependent (BOLD) functional MRI (fMRI) contrast requires the echo time of the MR sequence to match the T2* value of the tissue of interest, which is expected to be higher in the fetal brain compared with the brain of a child or an adult. METHODS T2* values of the cortical plate/cortical gray matter tissue in utero in healthy fetuses from mid-gestation onward (20-36 gestational weeks) were measured using 3D T2* maps calculated from 2D dual-echo T2… CONTINUE READING
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