3D heterogeneous islet organoid generation from human embryonic stem cells using a novel engineered hydrogel platform.

@article{Candiello20183DHI,
  title={3D heterogeneous islet organoid generation from human embryonic stem cells using a novel engineered hydrogel platform.},
  author={Joseph E Candiello and Taraka Sai Pavan Grandhi and Saik Kia Goh and Vimal Vaidya and Maya Lemmon-Kishi and Kiarash Rahmani Eliato and Robert Ros and Prashant N. Kumta and Kaushal Rege and Ipsita Banerjee},
  journal={Biomaterials},
  year={2018},
  volume={177},
  pages={
          27-39
        }
}
Organoids, which exhibit spontaneous organ specific organization, function, and multi-cellular complexity, are in essence the in vitro reproduction of specific in vivo organ systems. Recent work has demonstrated human pluripotent stem cells (hPSCs) as a viable regenerative cell source for tissue-specific organoid engineering. This is especially relevant for… CONTINUE READING