3D bioprinting of tissues and organs

@article{Murphy20143DBO,
  title={3D bioprinting of tissues and organs},
  author={Sean V. Murphy and Anthony J. Atala},
  journal={Nature Biotechnology},
  year={2014},
  volume={32},
  pages={773-785}
}
Additive manufacturing, otherwise known as three-dimensional (3D) printing, is driving major innovations in many areas, such as engineering, manufacturing, art, education and medicine. Recent advances have enabled 3D printing of biocompatible materials, cells and supporting components into complex 3D functional living tissues. 3D bioprinting is being applied to regenerative medicine to address the need for tissues and organs suitable for transplantation. Compared with non-biological printing… Expand
3D Bioprinting for Tissue Engineering
Three-dimensional (3D) printing, also referred to as additive manufacturing (AM), is being used widely in diverse areas, including manufacturing, food, art, and architecture. Recently, regenerativeExpand
Tissue Engineering Applications of Three-Dimensional Bioprinting
TLDR
3D bioprinting is yet to successfully overcome the many challenges related to building 3D structures that closely resemble native organs and tissues, which are complex structures with defined microarchitecture and a variety of cell types in a confined area. Expand
Bioprinting Complex 3D Tissue and Organs
TLDR
Advances in the development and application of various biomaterials, stem cell populations, and technical tools is allowing researchers, for the first time, to accurately reproduce the structure and function of the healthy tissues in vitro for future transplantation into patients with chronic kidney disease. Expand
3D Bioprinting: A Novel Avenue for Manufacturing Tissues and Organs
TLDR
3D bioprinting provides the unprecedented capacity of depositing various types of biomaterials, cells, and biomolecules in a layer-by-layer fashion, with precisely controlled spatial distribution, and is expected to address the organ-shortage issue in the future. Expand
3D bioprinting for engineering complex tissues.
TLDR
Combined with recent advances in human pluripotent stem cell technologies, 3D-bioprinted tissue models could serve as an enabling platform for high-throughput predictive drug screening and more effective regenerative therapies. Expand
3D Bioprinting in Tissue Engineering for Medical Applications: The Classic and the Hybrid
TLDR
This review provides an overview of recent advances in the development of 3D bioprinting techniques, particularly new hybrid 3DBiOPrinting technologies for combining the strengths of both AM and CM, along with a comprehensive set of material selection principles, promising medical applications, and limitations and future prospects. Expand
3D Printing for Tissue Engineering Applications
The goal of tissue engineering is to create functional tissues and organs for regenerative therapies, and total organ transplantation. Bioprinting tissues are one of the most attractive approachesExpand
3D Bioprinting of Vascularized Tissues for in vitro and in vivo Applications
TLDR
This discussion will begin with the exploration of printing vasculature, progress through the current statuses of bioprinting tissue/organoids from bone to muscles to organs, and conclude with relevant applications for in vitro models and drug testing. Expand
Three-dimensional bioprinting for bone and cartilage transplantation
TLDR
This study reviewed the recent advances in 3D bioprinting, as well as a general procedure, and reviewed the applications that aim to replace damaged bone and cartilage tissues, and research of in vitro tissue culture models. Expand
3D bioprinting technology for regenerative medicine applications
Alternative strategies that overcome existing organ transplantation methods are of increasing importance be-cause of ongoing demands and lack of adequate organ donors. Recent improvements in tissueExpand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 160 REFERENCES
Thermal inkjet printing in tissue engineering and regenerative medicine.
TLDR
This review article introduces some important patents related to bioprinting of living systems and the applications of biopprinting in tissue engineering field. Expand
Biomatrices and biomaterials for future developments of bioprinting and biofabrication.
TLDR
A direct 3D cell printing system using inkjet and gelation techniques with inkjet droplets is developed, and it is found that it had good potential to construct 3D structures with multiple types of cells. Expand
Toward engineering functional organ modules by additive manufacturing.
TLDR
This work describes the technology and its specific applications to engineer vascular and nerve grafts and briefly overview some of the scaffold-free approaches and detail one that employs biological self-assembly and bioprinting. Expand
Bioprinting of hybrid tissue constructs with tailorable mechanical properties.
TLDR
An innovative and versatile approach for bioprinting is presented, yielding constructs of which the mechanical stiffness provided by thermoplastic polymers can potentially be tailored, and combined specific cell placement patterns of multiple cell types embedded in a wide range of hydrogels. Expand
Biopolymer deposition for freeform fabrication of hydrogel tissue constructs
Three-dimensional (3D) tissue scaffolds play a vital role as extra-cellular matrices onto which cells can attach, grow, and form new tissue. Among available biomaterials, hydrogels, such as alginate,Expand
Hybrid printing of mechanically and biologically improved constructs for cartilage tissue engineering applications.
TLDR
This study demonstrates the feasibility of constructing a hybrid inkjet printing/electrospinning system using off-the-shelf components to produce cartilage constructs with improved biological and mechanical properties. Expand
Scaffold-free vascular tissue engineering using bioprinting.
TLDR
A fully biological self-assembly approach, which is implemented through a rapid prototyping bioprinting method for scaffold-free small diameter vascular reconstruction and has the ability to engineer vessels of distinct shapes and hierarchical trees that combine tubes of distinct diameters. Expand
Direct-write bioprinting three-dimensional biohybrid systems for future regenerative therapies.
TLDR
This review describes the current state-of-the-art bioprinting technologies and provides baseline direct-write printing parameters for a hydrogel system often used in cardiovascular applications to provide a useful foundation for colleagues to incorporate this 3D fabrication method into future regenerative therapies. Expand
25th anniversary article: Engineering hydrogels for biofabrication.
TLDR
The deposition process, the parameters and demands of hydrogels in biofabrication, with special attention to robotic dispensing as an approach that generates constructs of clinically relevant dimensions are focused on. Expand
Direct human cartilage repair using three-dimensional bioprinting technology.
TLDR
The importance of direct cartilage repair and promising anatomic cartilage engineering using 3D bioprinting technology is indicated and the need to integrate implants with surrounding native tissues is highlighted. Expand
...
1
2
3
4
5
...