3D QSAR STUDIES OF INHIBITORS OF CHOLESTEROL ESTER TRANSFER PROTEIN (CETP) BY CoMFA, CoMSIA AND GFA METHODOLOGIES

Abstract

CETP is a plasma glycoprotein that mediates the transfer of cholesterol ester (CE) from high-density lipoprotein (HDL) to apolipoprotein-B containing lipoproteins such as very low density lipoproteins (VLDL) and low density lipoprotein (LDL) with a balanced exchange of triglycerides. CETP thus plays a potential pro-atherogenic role by moving CE from HDL… (More)
DOI: 10.1007/s00044-004-0104-9

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@article{Kelkar20043DQS, title={3D QSAR STUDIES OF INHIBITORS OF CHOLESTEROL ESTER TRANSFER PROTEIN (CETP) BY CoMFA, CoMSIA AND GFA METHODOLOGIES}, author={Mandar A. Kelkar and Deepa V. Pednekar and Surekha R. Pimple and Krishnacharya G. Akamanchi}, journal={Medicinal Chemistry Research}, year={2004}, volume={13}, pages={590-604} }