3D Bone tissue engineered with bioactive microspheres in simulated microgravity

@article{Qiu20013DBT,
  title={3D Bone tissue engineered with bioactive microspheres in simulated microgravity},
  author={Qing-Qing Qiu and Paul Ducheyne and PORTONOVO S. AYYASWAMY},
  journal={In Vitro Cellular & Developmental Biology - Animal},
  year={2001},
  volume={37},
  pages={157-165}
}
SummaryThree-dimensional (3D) osteoblast cell cultures were obtained in rotating-wall vessels (RWV), simulating microgravity. Three types of bioactive microcarriers, specifically modified bioactive glass particles, bioceramic hollow microspheres, and biodegradable bioactive glass-polymer composite microspheres, were developed and used with osteblasts. The surfaces of composite microspheres fully transformed into bone apatite after 2-wk immersion in simulated physiological fluid, which… CONTINUE READING

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