3D-3-culture: A tool to unveil macrophage plasticity in the tumour microenvironment.

Abstract

The tumour microenvironment (TME) shapes disease progression and influences therapeutic response. Most aggressive solid tumours have high levels of myeloid cell infiltration, namely tumour associated macrophages (TAM). Recapitulation of the interaction between the different cellular players of the TME, along with the extracellular matrix (ECM), is critical… (More)
DOI: 10.1016/j.biomaterials.2018.02.030

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