38 Pharmacokinetics , Pharmacodynamics , and Drug Disposition

  title={38 Pharmacokinetics , Pharmacodynamics , and Drug Disposition},
  author={David J Greenblatt and Lisa L. von Moltke and Jerold S. Harmatz and Richard},
During the last decade, the application of pharmacokinetic and pharmacodynamic modeling techniques has become an increasingly important aspect of contemporary clinical psychopharmacology (1–5). These techniques have been applied during the process of development of new drug entities as well as for the improved understanding of the clinical actions of drugs that are already marketed. Techniques for the study of drug metabolism in vitro have advanced substantially during the last decade, and now… CONTINUE READING