-344C/T polymorphism of CYP11B2 gene in Italian patients with idiopathic low renin hypertension.

@article{Rossi2001344CTPO,
  title={-344C/T polymorphism of CYP11B2 gene in Italian patients with idiopathic low renin hypertension.},
  author={Ermanno Rossi and Giuseppe Regolisti and Franco Perazzoli and Aurelio Negro and Simona Davoli and Davide Nicoli and Carlo Sani and Bruno Casali},
  journal={American journal of hypertension},
  year={2001},
  volume={14 9 Pt 1},
  pages={934-41}
}
Most patients with low renin essential hypertension are not qualitatively different from patients with idiopathic hyperaldosteronism, as in both conditions aldosterone secretion is not appropriately reduced. The aim of the study was to investigate allele and genotype frequencies of the -344C/T polymorphism, located in the promoter region of the aldosterone synthase gene, in 83 patients with idiopathic low renin hypertension characterized by an increased aldosterone to renin ratio, including… CONTINUE READING
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