31P nuclear magnetic resonance study of the brain in Alzheimer's disease.

@article{Pettegrew198831PNM,
  title={31P nuclear magnetic resonance study of the brain in Alzheimer's disease.},
  author={Jay W. Pettegrew and John J. Moossy and Graham Withers and D B Mckeag and Kanagasabai Panchalingam},
  journal={Journal of neuropathology and experimental neurology},
  year={1988},
  volume={47 3},
  pages={235-48}
}
The histopathological hallmarks of Alzheimer's disease have long been considered to be neurofibrillary tangles (NFT) and neuritic (senile) plaques (SP). Neither of these structures, however, are unique to Alzheimer's disease, and both probably represent end-stage markers of the disorder. NFT have been demonstrated in many disorders; SP occur in small numbers with normal aging. Evidence is presented for elevation of phosphomonoesters (PME) in Alzheimer's brain compared to non-Alzheimer's… CONTINUE READING
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