31P magnetic resonance spectroscopy in the frontal lobe of major depressed patients

@article{Volz199831PMR,
  title={31P magnetic resonance spectroscopy in the frontal lobe of major depressed patients},
  author={H P Volz and Reinhard Rzanny and Stefan Riehemann and Susanne May and Helmut Hegewald and Birgitt Preussler and Gabriele H{\"u}bner and Werner A. Kaiser and Heinrich Sauer},
  journal={European Archives of Psychiatry and Clinical Neuroscience},
  year={1998},
  volume={248},
  pages={289-295}
}
Most research with 31P-magnetic resonance spectroscopy (31P-MRS) in affective disorders has been done in the field of bipolar disturbances. Reduced frontal and temporal lobe phosphomonoester (PME) concentrations were measured in the euthymic state, whereas increased values were found in the depressed state. In bipolar-II patients reduced phosphocreatine (PCr) concentrations were reported in the euthymic, depressed, and manic state. The aim of the present study was to explore whether PME and PCr… CONTINUE READING