31P-NMR spectroscopy of human blood and serum: first results from volunteers and patients with congestive heart failure, diabetes mellitus and hyperlipidaemia

@article{Horn200531PNMRSO,
  title={31P-NMR spectroscopy of human blood and serum: first results from volunteers and patients with congestive heart failure, diabetes mellitus and hyperlipidaemia},
  author={Michael Horn and Stefan Neubauer and Michael Bomhard and Marcus Kadgien and Klaus D Schnackerz and Georg Ertl},
  journal={Magma},
  year={2005},
  volume={1},
  pages={55-60}
}
31P-containing metabolites in human blood, serum and erythrocytes were measured or calculated. Phosphodiesters were found in serum, but not in erythrocytes. 2,3-diphosphoglycerate and 2,3-diphosphoglycerate/ATP ratios were increased in patients with congestive heart failure (2,3-diphosphoglycerate by 13% in mild to moderate, 31% in severe congestive heart failure, 2,3-diphosphoglycerate/ATP ratio by 9% in mild to moderate, 38% in severe congestive heart failure); phosphodiesters were increased… CONTINUE READING