31P-NMR-measured creatine kinase reaction flux in muscle: a caveat!

  title={31P-NMR-measured creatine kinase reaction flux in muscle: a caveat!},
  author={Theo Wallimann},
  journal={Journal of Muscle Research & Cell Motility},
The creatine kinase (CK) isoenzyme family (E.C., catalyzing the reversible phosphoryl transfer from phospho-creatine (PCr) to ADP, represents an important enzyme system for cellular energy homeostasis in cells with high and fluctuating energy requirements. Results obtained by cell-biological/ biochemical approaches have revealed the CK system as a highly compartmentalized and complex energy buffering, distribution and regulatory network (see Wallimann et al., 1989; 1992; Ventura… CONTINUE READING