31 in Vivo Molecular Imaging : Ligand Development and Research Applications

  title={31 in Vivo Molecular Imaging : Ligand Development and Research Applications},
  author={MASAHIRO FUMITA and Robert B. Innis},
In positron emission tomography (PET) and single-photon emission computed tomography (SPECT), tracers labeled with radioactive isotopes are used to measure protein molecules (e.g., receptors, transporters, and enzymes). A major advantage of these two radiotracer techniques is extraordinarily high sensitivity ( 10 9 to 10 12 M), many orders of magnitude greater than the sensitivities available with magnetic resonance imaging (MRI) ( 10 4 M) or magnetic resonance spectroscopy (MRS) ( 10 3 to 10 5… CONTINUE READING


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