3039 Metabolic flux analysis of acetylcarnitine turnover and mitochondrial oxidation of [ 2-13 C ] acetate in rat skeletal muscle in vivo measured by 13 C MRS

@inproceedings{Bastiaansen20133039MF,
  title={3039 Metabolic flux analysis of acetylcarnitine turnover and mitochondrial oxidation of [ 2-13 C ] acetate in rat skeletal muscle in vivo measured by 13 C MRS},
  author={Jessica A M Bastiaansen and Jo{\~a}o M. N. Duarte and Rolf Gruetter},
  year={2013}
}
INTRODUCTION: Acetylcarnitine is a necessary intermediate in the mitochondrial oxidation of acetate, since it transports the acetyl moiety across the mitochondrial membrane [1]. It has only been observed using hyperpolarized methods [2,3] or with localized polarization transfer sequences [5]. Glutamate has been used as an indicator of citric acid cycle (TCA… CONTINUE READING