• Corpus ID: 3455581

300 CHAPTER 10 Posterior Pituitary

  title={300 CHAPTER 10 Posterior Pituitary},
  author={Alan G. Robinson and Joseph G Verbalis},
• The posterior pituitary is neural tissue and consists only of the distal axons of the hypothalamic magnocellular neurons that make up the neurohypophysis. • The control of hormone synthesis is at the level of transcription. Stimuli for secretion of vasopressin or oxytocin also stimulate transcription and increase the messenger ribonucleic acid (mRNA) content in the magnocellular neurons. • The physiologic regulation of vasopressin synthesis and secretion involves two systems: osmotic and… 


Paraventricular nucleus: a site for the integration of neuroendocrine and autonomic mechanisms.
The evidence indicates that subpopulations of neurons in the PVH are directly related to autonomic and neuroendocrine effector mechanisms, and suggest that the nucleus plays an important role in the regulation of visceral responses in the periphery and in the CNS itself.
Morphology of vasopressin and oxytocin neurones and their central and vascular projections.
The hypothalamic-pituitary axis: co-development of two organs.
Functional Consequences of Morphological Neuroglial Changes in the Magnocellular Nuclei of the Hypothalamus
  • S. Oliet
  • Biology
    Journal of neuroendocrinology
  • 2002
It thus appears that the structural plasticity of the magnocellular nuclei does affect neuroglial interactions, inducing significant changes in signal transmission and processing.
Vasopressin and oxytocin release during prolonged environmental hypoxia in the rat.
An increase in hypothalamic production of vasopressin and oxytocin in rats during prolonged hypoxaemia is demonstrated, which suggests that compensatory mechanisms modulate the actions of both vasopressed hormones.
Glutamatergic Inputs Contribute to Phasic Activity in Vasopressin Neurons
The data strongly suggest that phasic activity in magnocellular VP neurons is controlled by glutamatergic synaptic inputs rather than by intrinsic properties.
Targeted reduction of oxytocin expression provides insights into its physiological roles.
There is an absolute requirement for oxytocin for successful milk ejection, but not for mating, parturition and milk production, in mice, and homozygous mutant mice show reduced aggression in some tests.
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  • J. Evans
  • Biology
    European journal of endocrinology
  • 1997
This review considers effects induced by oxytocin which have been observed in human studies, and considers some of the processes which control interaction between physiological units, to point to the multifaceted effects, including alterations of behaviour, a pathological change can have.