3.6 kb genomic sequence from Takifugu capable of promoting axon growth-associated gene expression in developing and regenerating zebrafish neurons.

@article{Udvadia200836KG,
  title={3.6 kb genomic sequence from Takifugu capable of promoting axon growth-associated gene expression in developing and regenerating zebrafish neurons.},
  author={Ava J. Udvadia},
  journal={Gene expression patterns : GEP},
  year={2008},
  volume={8 6},
  pages={
          382-8
        }
}
Unlike mammals, fish have the capacity for functional adult CNS regeneration, which is due, in part, to their ability to express axon growth-related genes in response to nerve injury. One such axon growth-associated gene is gap43, which is expressed during periods of developmental and regenerative axon growth, but is not expressed in CNS neurons that do not regenerate in adult mammals. We previously demonstrated that cis-regulatory elements of gap43 that are sufficient for developmental… CONTINUE READING

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The Zebrafish Book: A Guide for the Laboratory Use of Zebrafish (Danio rerio)

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1 Excerpt