3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors reduce the risk of perioperative stroke and mortality after carotid endarterectomy.

@article{McGirt20053hydroxy3methylglutarylCA,
  title={3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors reduce the risk of perioperative stroke and mortality after carotid endarterectomy.},
  author={Matthew J. McGirt and Bruce A. Perler and Benjamin S. Brooke and Graeme F Woodworth and Alexander L Coon and Shamik K. Jain and Donald W. Buck and Glen S Roseborough and Rafael John Tamargo and Jennifer K Heller and Julie Ann Freischlag and George Melville Williams},
  journal={Journal of vascular surgery},
  year={2005},
  volume={42 5},
  pages={829-36; discussion 836-7}
}
OBJECTIVE There is increasing evidence that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) reduce cardiovascular and cerebrovascular events through anti-inflammatory, plaque stabilization, and neuroprotective effects independent of lipid lowering. This study was designed to investigate whether statin use reduces the incidence of perioperative stroke and mortality among patients undergoing carotid endarterectomy (CEA). METHODS All patients undergoing CEA from 1994 to 2004… CONTINUE READING

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