3-Methoxysampangine, a novel antifungal copyrine alkaloid from Cleistopholis patens

  title={3-Methoxysampangine, a novel antifungal copyrine alkaloid from Cleistopholis patens},
  author={S. C. Liu and Babajide O. Oguntimein and Charles D. Hufford and Alice Mae Clark},
  journal={Antimicrobial Agents and Chemotherapy},
  pages={529 - 533}
Further examination of the active ethanolic extract of the root bark of Cleistopholis patens by using bioassay-directed fractionation resulted in the isolation of a new alkaloid, 3-methoxysampangine (compound I), together with three known alkaloids, eupolauridine (compound II), liriodenine (compound III), and eupolauridine N-oxide (compound IV). The proposed structure of compound I was based on its physicochemical properties and spectral data. 3-Methoxysampangine exhibited significant… 
8-Hydroxysampangine, A New Alkaloid Isolated From Cleistopholis Patens (Annonaceae)
Abstract A new 1-azaoxoaporphinoid alkaloid, 8-hydroxysampangine (1), was isolated from the trunk bark of Cleistopholis patens (Annonaceae), a medicinal plant used in Gabonese traditional medicine.
Antifungal activity of berberine iodide, a constituent ofFumaria indica
Berberine iodide, an isoquinoline alkaloid was isolated fromFumaria indica and its efficacy was tested against spore germination of some plant parasitic as well as saprophytic fungi. The alkaloid
Antifungal activity of Δ3-alstovenine, a plant alkaloid isolated fromAlstonia venenata
A plant quaternary alkaloid Δ3-alstovenine inhibited the spore germination of most of the fungi tested at concentration of 250–1000 mg/L. Saprophytic and biotrophic fungi were equally sensitive to
Antifungal copyrine alkaloids: crystal structure of 3-methylsampangine
Abstract3-Methylsampangine, C16H10N2O, crystallizes in the monoclinic space group P21/c witha=7.260(3),b=10.697(5),c=15.342(6) Å, and β=102.69(4). All nonhydrogen atoms of this potent antifungal
Some alkaloids and flavonoids from Cissampelos capensis
The crude fractions and isolates were tested for cytotoxicity using the brine shrimp lethality test and for antimicrobial properties using nine microbes, including three Gram –ve, three Gram +ve bacteria and three fungi.
Inhibitory Effect of Two Alkaloids, (–)-Corydalmine and (–)-Isocorypalmine Isolated from Corydalis chaerophylla on Several Phytopathogenic Fungi
The effect of two alkaloids, (—)-corydalmine and (—-isocorypalmine isolated from Corydalis chaerophylla, against spore germination of some plant pathogenic and saprophytic fungal spores is investigated.


Two antimicrobial alkaloids from heartwood of Liriodendron tulipifera L.
Alcoholic extracts of the heartwood of Liriodendron tulipifera have demonstrated antimicrobial activity against Staphylococcus aureus, Mycobacterium smegmatis, Candida albicans, and Aspergillus
Antifungal activity of Trillium grandiflorum constituents.
EtOH extracts of the rhizomes and aboveground portion of Trillium grandiflorum showed significant antifungal activity, leading to the identification of the active components as the saponin glycosides 1 and 3.
Antimicrobial activity of phenolic constituents of Magnolia grandiflora L.
Three phenolic constituents of Magnolia grandiflora L. were shown to possess significant antimicrobial activity using an agar well diffusion assay and the minimum inhibitory concentrations were determined.
Polycyclische aromatische Alkaloide, I. Synthese von Cleistopholin und Sampangin
Polycyclic Aromatic Alkaloids, I. - Synthesis of Cleistopholine and Sampangine Cleistopholine (4) is prepared in a one-pot synthesis by Diels-Alder cycloaddition of 1 to 2, followed by thermal
X-Ray crystal structure of canellal, a novel antimicrobial sesquiterpene from Canella winterana
Canellal (1), a novel antimicrobial sesquiterpene dialdehyde, has been isolated from the trunk bark of Canella winterana; its structure and stereochemistry were determined from spectral and
Medicinal plants in tropical West Africa. III. Anti-infection therapy with higher plants.
Anticandidal activity of eupolauridine and onychine, alkaloids from Cleistopholis patens.
Sampangine, a new alkaloid from Cananga odorata