By use of broad bandwidth light source, the potential of OCT is demonstrated to perform noninvasive optical biopsy of the human retina (D. Huang, et al, 1991). OCT is based on low coherence interferometry (R. C. Youngquist, et al, 1987), in which the pattern of interference between the reference and object beams is used to determine the amount of light reflected back from a certain point within the volume of the sample under study. The broad bandwidth source is used for illumination, so the two beams only produce an interference pattern when their optical paths difference is less than the coherence length of the source. This means that the bandwidth of the source determines the axial resolution of the OCT system. Therefore, by using ultra-broad bandwidth light source (such as Ti: Al2O3 laser, laser generated from a photo crystal fiber, ultra-broadband SLD), the cross section image as biopsy is achieved successfully(A. Unterhuber, et al, 2003, Yimin Wang, et al, 2003, D.S. Adler, et al, 2004).