3-(2-Bromoethyl)-indole inhibits the growth of cancer cells and NF-κB activation

Abstract

Indole-3-carbinol (I3C) and diindolylmethane (DIM), found in cruciferous vegetables, have chemopreventive and anticancer properties. In the present study, 14 substituted indoles were tested for activity against SW480 colon cancer cells. Among these, 3-(2-bromoethyl)-indole, named BEI-9, showed the greatest inhibition. The effects of BEI-9 on cancer cells… (More)
DOI: 10.3892/or.2015.3970

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