3'-Aminoadenosine-5'-uronamides: discovery of the first highly selective agonist at the human adenosine A3 receptor.

@article{Deninno20033Aminoadenosine5uronamidesDO,
  title={3'-Aminoadenosine-5'-uronamides: discovery of the first highly selective agonist at the human adenosine A3 receptor.},
  author={Michael Paul Deninno and Hiroko Masamune and Lois K Chenard and Kenneth J Dirico and Cynthia Eller and John B Etienne and Jeanene E Tickner and Scott P. Kennedy and Delvin R. Knight and Jimmy X Kong and Joseph J. Oleynek and William R. Tracey and Roger J. Hill},
  journal={Journal of medicinal chemistry},
  year={2003},
  volume={46 3},
  pages={
          353-5
        }
}
Selective adenosine A(3) agonists have potential utility for the prevention of perioperative myocardial ischemic injury. Herein, we report on the discovery and synthesis of compound 7. This amino nucleoside agonist possesses unprecedented levels of selectivity for the human adenosine A(3) receptor. 
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