3,6-O-[N-(2-Aminoethyl)-acetamide-yl]-chitosan exerts antibacterial activity by a membrane damage mechanism.

Abstract

A novel chitosan derivative, 3,6-O-[N-(2-aminoethyl)-acetamide-yl]-chitosan (AACS), was successfully prepared to improve water solubility and antibacterial activity of chitosan. AACS had good antibacterial activity, with minimum inhibitory concentrations of 0.25mg/mL, against Escherichia coli and Staphylococcus aureus. Cell membrane integrity, electric… (More)
DOI: 10.1016/j.carbpol.2016.04.098

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Cite this paper

@article{Yan201636ON2AminoethylacetamideylchitosanEA, title={3,6-O-[N-(2-Aminoethyl)-acetamide-yl]-chitosan exerts antibacterial activity by a membrane damage mechanism.}, author={Feilong Yan and Q. K. Dang and Chengsheng Liu and Jingquan Yan and Teng Wang and Bing Fan and Dongsu Cha and Xiaoli Li and Shengnan Liang and Zhenzhen Zhang}, journal={Carbohydrate polymers}, year={2016}, volume={149}, pages={102-11} }