3,3-Bisaryloxindoles as mineralocorticoid receptor antagonists.


Syntheses and SAR studies of 3,3-bisaryloxindole analogues provided potent mineralocorticoid receptor (MR) antagonists that were selective over other steroid nuclear hormone receptors. 


Cite this paper

@article{Neel200533BisaryloxindolesAM, title={3,3-Bisaryloxindoles as mineralocorticoid receptor antagonists.}, author={David A Neel and Matthew L. Brown and Peter A Lander and Timothy A Grese and Jean M Defauw and Robert A Doti and T. J. Fields and Sally Ann Kelley and Stephon C Smith and Karen Zimmerman and Mitchell I. Steinberg and Prabhakar K. Jadhav}, journal={Bioorganic & medicinal chemistry letters}, year={2005}, volume={15 10}, pages={2553-7} }