3'-phosphoinositides regulate the coordination of speed and accuracy during chemotaxis.

@article{Gruver20083phosphoinositidesRT,
  title={3'-phosphoinositides regulate the coordination of speed and accuracy during chemotaxis.},
  author={Jeffrey Gruver and John P. Wikswo and Chang Y. Chung},
  journal={Biophysical journal},
  year={2008},
  volume={95 8},
  pages={4057-67}
}
The PI3K/PTEN pathway, as the regulator of 3'-phosphoinositide (3'-PI) dynamics, has emerged as a key regulator of chemoattractant gradient sensing during chemotaxis in Dictyostelium and other cell types. Previous results have shown 3'-PIs to be important for regulating basal cell motility and sensing the direction and strength of the chemoattractant… CONTINUE READING