3' cap-independent translation enhancers of plant viruses.

  title={3' cap-independent translation enhancers of plant viruses.},
  author={Anne E Simon and W. Allen Miller},
  journal={Annual review of microbiology},
In the absence of a 5' cap, plant positive-strand RNA viruses have evolved a number of different elements in their 3' untranslated region (UTR) to attract initiation factors and/or ribosomes to their templates. These 3' cap-independent translational enhancers (3' CITEs) take different forms, such as I-shaped, Y-shaped, T-shaped, or pseudoknotted structures, or radiate multiple helices from a central hub. Common features of most 3' CITEs include the ability to bind a component of the translation… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 63 extracted citations


Publications referenced by this paper.
Showing 1-10 of 71 references

First demonstration that T-shaped structures form in an internal position in the 3′ UTR of a viral RNA

  • JC McCormack, X Yuan, YG Yingling, W Kasprzak, RE Zamora
  • J. Virol
  • 2008
Highly Influential
20 Excerpts

Demonstrated binding of the CIRV YSS to eIF4F and eIFiso4F and that YSS can be functionally replaced by the PTE or ISS 3′ CITE

  • BL Nicholson, O Zaslaver, LK Mayberry, KS Browning, KA. White
  • J. Virol
  • 2013
Highly Influential
7 Excerpts

Showed that the ISS 3′ CITE can simultaneously bind to eIF4F and the 5′ UTR and that this complex is required for recruiting ribosomes to the 5′ end of the viral RNA genome

  • BL Nicholson, B Wu, I Chevtchenko, KA. White
  • RNA
  • 2010
Highly Influential
6 Excerpts

First analysis of how a 3′ CITE (PEMV2 PTE) interacts with a bound translation initiation factor, leading to a new mechanism for mRNA recognition by elF4E

  • Z Wang, M Parisien, K Scheets, WA. Miller
  • Structure
  • 2011
Highly Influential
3 Excerpts

First demonstration that ribosomes can bind to 3′ CITEs and that binding is important for translational enhancement

  • VA Stupina, A Meskauskas, JC McCormack, YG Yingling, BA Shapiro
  • RNA
  • 2008
Highly Influential
5 Excerpts

Similar Papers

Loading similar papers…