2D Inorganic-Antimalarial Drug-Polymer Hybrid with pH-Responsive Solubility.

Abstract

Artesunic acid (ASH), an antimalarial drug, has low oral bioavailability due to its low aqueous solubility. To overcome this problem, artesunate (AS) was intercalated into zinc basic salt (ZBS) via co-precipitation. AS was immobilized with a tilted double layer arrangement, which was also confirmed by XRD and 1-D electron density mapping. In order to… (More)
DOI: 10.1002/asia.201500347

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