2D-DIGE to identify proteins associated with gestational diabetes in omental adipose tissue.

@article{Oliva20132DDIGETI,
  title={2D-DIGE to identify proteins associated with gestational diabetes in omental adipose tissue.},
  author={Karen T. Oliva and Gillian M Barker and Gregory Rice and Mark J. Bailey and Martha Lappas},
  journal={The Journal of endocrinology},
  year={2013},
  volume={218 2},
  pages={165-78}
}
Gestational diabetes mellitus (GDM) is a significant risk factor for the type 2 diabetes epidemic in many populations. Maternal adipose tissue plays a central role in the pathophysiology of GDM. Thus, the aim of this study was to determine the effect of GDM on the proteome of adipose tissue. Omental adipose tissue was obtained at the time of term Caesarean section from women with normal glucose tolerance (NGT) or GDM. 2D-difference gel electrophoresis (DIGE), followed by mass spectrometry, was… CONTINUE READING
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