289 Insulin Inhibits the Synthesis of the Major Surfactant Apoprotein in Human Fetal Lung in Vitro

Abstract

Fetal hyperinsulinemia may be a causative factor in the increased incidence of respiratory distress syndrome (RDS) in newborn infants of diabetic mothers. We previously observed, however, that insulin acted synergistically with cortisol to increase disaturated phosphatidylcholine synthesis in human fetal lung explants in vitro. Surfactant apoproteins, which… (More)
DOI: 10.1203/00006450-198504000-00319

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@article{Mendelson1985289II, title={289 Insulin Inhibits the Synthesis of the Major Surfactant Apoprotein in Human Fetal Lung in Vitro}, author={Carole R. Mendelson and Jeanne M. Snyder and Cheryl R Rosenfeld}, journal={Pediatric Research}, year={1985}, volume={19}, pages={159A-159A} }