251 Effects of Ibuprofen and Indomethacin on VEGF, IGF-I, and GH in the Rat Retina, Vitreous, and Serum

Abstract

Background/Aims: IB and IN have been shown to improve oxygen-induced retinopathy in mice. The effects of IB and IN on VEGF, IGF-I, and GH (regulators of growth and retinal development) have not been studied. We hypothesized that the effects of IB and IN are partly mediated via their action on these growth factors.Methods: Newborn rats (n=3 litters/group; 15… (More)
DOI: 10.1203/00006450-200508000-00280

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