25-Hydroxyvitamin D concentrations in children with Crohn's disease supplemented with either 2000 or 400 IU daily for 6 months: a randomized controlled study.

@article{Wingate201425HydroxyvitaminDC,
  title={25-Hydroxyvitamin D concentrations in children with Crohn's disease supplemented with either 2000 or 400 IU daily for 6 months: a randomized controlled study.},
  author={Kirstin Emma Wingate and Kevan Jacobson and Robert M. Issenman and Matthew W. Carroll and Collin C. Barker and David M. Israel and Herbert Brill and Hope Alberta Weiler and Susan I Barr and Wangyang Li and Michael R. Lyon and Timothy J Green},
  journal={The Journal of pediatrics},
  year={2014},
  volume={164 4},
  pages={
          860-5
        }
}
OBJECTIVES To assess vitamin D status of pediatric patients with Crohn's disease (CD) and to compare their serum 25-hydroxyvitamin D (s-25OHD) with established cutoffs and assess whether 6 months of supplementation with 2000 IU/d, vs 400 IU/d, would reduce the group prevalence of vitamin D below these cutoffs. STUDY DESIGN Subjects 8-18 years (n = 83) with quiescent CD were randomized to either 400 or 2000 IU vitamin D3/d for 6 months. RESULTS Baseline mean ± SD s-25OHD was 24 ± 8 ng/mL; 13… CONTINUE READING
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