25-Hydroxyvitamin D Metabolism in the Sheep Fetus and Lamb

Abstract

SUMMARY: The metabolism of [3H]-25-hydroxyvitamin D3(3H-25-OH-D3)to [3H]-1,25-dihydroxyvitamin D3 (3H-1,25-(OH)2D3J3 and[3H]-24, 25 dihydroxyvitamin D3 (3H-24,25-(OH)2D3) was studied in sheep fetuses and lambs. In vivo metabolism was observed by chromatography of extracts of plasma obtained 24 hr after direct iv injection of 3H-25-OH-D3 to the fetus and… (More)
DOI: 10.1203/00006450-198004000-00022

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