200th anniversary of lactate research in muscle.

  • L. Gladden
  • Published 2008 in Exercise and sport sciences reviews

Abstract

This year, 2008, marks the bicentennial of research into lactate metabolism in muscle. Berzelius linked lactate accumulation to exercise in 1807/1808 when he noted the presence of lactate in the muscles of "hunted stags." Today, the exact mechanism of intramuscular lactate oxidation and the relationship of lactate dehydrogenase to mitochondria remain… (More)
DOI: 10.1097/JES.0b013e31817c0038

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