20-Residue and 11-residue peptaibols from the fungus Trichoderma longibrachiatum are synergistic in forming Na+/K+ -permeable channels and adverse action towards mammalian cells.

@article{Mikkola201220ResidueA1,
  title={20-Residue and 11-residue peptaibols from the fungus Trichoderma longibrachiatum are synergistic in forming Na+/K+ -permeable channels and adverse action towards mammalian cells.},
  author={Raimo Mikkola and Maria A. Andersson and L{\'a}szl{\'o} Kredics and Pavel A Grigoriev and Nina Sundell and Mirja S. Salkinoja-Salonen},
  journal={The FEBS journal},
  year={2012},
  volume={279 22},
  pages={4172-90}
}
Certain species of the filamentous fungal genus Trichoderma (e.g. Trichoderma longibrachiatum and Trichoderma citrinoviride) are among the emerging clinical pathogens and also the most common species in the indoor space of mould-damaged buildings. The molecules involved in its pathology are not known. In the present study, we report that 0.5-2.6 wt% of the T. longibrachiatum mycelial biomass consisted of thermostable secondary metabolites mitochondriotoxic to mammalian cells. These were… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 5 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 52 references

The production of multiple small peptaibol families by single 14-module peptide synthetases in Trichoderma/Hypocrea

  • T Degenkolb, R Karimi Aghcheh, +6 authors H von Döhren
  • Chem Biodivers
  • 2012

Trichoderma. In The Molecular Detection

  • Z Antal
  • 2011

Similar Papers

Loading similar papers…