2-diethylaminoethyl-dextran methyl methacrylate copolymer nonviral vector: still a long way toward the safety of aerosol gene therapy

@article{Zarogoulidis20132diethylaminoethyldextranMM,
  title={2-diethylaminoethyl-dextran methyl methacrylate copolymer nonviral vector: still a long way toward the safety of aerosol gene therapy},
  author={Paul Zarogoulidis and Wolfgang Hohenforst-Schmidt and Kaid Darwiche and Leslie Krauss and D Sparopoulou and Leonidas Sakkas and Andreas Gschwendtner and H Huang and Francis J Turner and Lutz Freitag and Konstantinos Zarogoulidis},
  journal={Gene Therapy},
  year={2013},
  volume={20},
  pages={1022-1028}
}
Revealing the lung tumor genome has directed the current treatment strategies toward targeted therapy. First line treatments targeting the genome of lung tumor cells have been approved and are on the market. However, they are limited by the small number of patients with the current investigated genetic mutations. Novel treatment administration modalities have been also investigated in an effort to increase the local drug deposition and disease control. In the current study, we investigated the… CONTINUE READING
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